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Substance P (1-7)(TFA)
CAS No. ——
Substance P (1-7)(TFA) ( Substance P (1-7) Trifluoroacetate )
Catalog No. M29733 CAS No. ——
Substance P (1-7)(TFA) is a fragment of the neuropeptide, substance P (SP).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameSubstance P (1-7)(TFA)
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NoteResearch use only, not for human use.
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Brief DescriptionSubstance P (1-7)(TFA) is a fragment of the neuropeptide, substance P (SP).
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DescriptionSubstance P (1-7)(TFA) is a fragment of the neuropeptide, substance P (SP).(In Vivo):Substance P (1-7) is found to act as a very potent antagonist against the SP-induced responses and is formed locally in the nigra after SP injection. It is proposed that Substance P (1-7) is an endogenous modulator of SP actions. Injection of low doses of Substance P (1-7) (1.0-4.0 pM simultaneously with SP or SP(5-11) (0.1 nM), reduce aversive behaviours induced by SP or SP(5- 11) significantly. These results indicate that SP(1-7) formed endogenously could modulate the actions of SP or SP(5-11) in the spinal cord.
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In Vitro——
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In Vivo——
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SynonymsSubstance P (1-7) Trifluoroacetate
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight1014.06
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Molecular FormulaC43H66F3N13O12
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Purity>98% (HPLC)
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SolubilityH2O : 50 mg/mL (49.31 mM; Need ultrasonic)
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SMILES——
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Chemical NameSequence:Arg-Pro-Lys-Pro-Gln-Gln-Phe
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
Herrera-Marschitz M, et al. The substance P(1-7) fragment is a potent modulator of substance P actions in the brain. Brain Res. 1990 Jun 25;521(1-2):316-20.
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