Substance P (1-7)(TFA)

CAS No.

Substance P (1-7)(TFA) ( Substance P (1-7) Trifluoroacetate )

Catalog No. M29733 CAS No.

Substance P (1-7)(TFA) is a fragment of the neuropeptide, substance P (SP).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Substance P (1-7)(TFA)
  • Note
    Research use only, not for human use.
  • Brief Description
    Substance P (1-7)(TFA) is a fragment of the neuropeptide, substance P (SP).
  • Description
    Substance P (1-7)(TFA) is a fragment of the neuropeptide, substance P (SP).(In Vivo):Substance P (1-7) is found to act as a very potent antagonist against the SP-induced responses and is formed locally in the nigra after SP injection. It is proposed that Substance P (1-7) is an endogenous modulator of SP actions. Injection of low doses of Substance P (1-7) (1.0-4.0 pM simultaneously with SP or SP(5-11) (0.1 nM), reduce aversive behaviours induced by SP or SP(5- 11) significantly. These results indicate that SP(1-7) formed endogenously could modulate the actions of SP or SP(5-11) in the spinal cord.
  • Synonyms
    Substance P (1-7) Trifluoroacetate
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    --
  • Formula Weight
    1014.1
  • Molecular Formula
    C43H66F3N13O12
  • Purity
    >98% (HPLC)
  • Solubility
    H2O : 50 mg/mL (49.31 mM; Need ultrasonic)
  • SMILES
    ——
  • Chemical Name

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Herrera-Marschitz M, et al. The substance P(1-7) fragment is a potent modulator of substance P actions in the brain. Brain Res. 1990 Jun 25;521(1-2):316-20.
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